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Description

 MDPV ?

buy MDPV ,(Methylenedioxypyrovalerone) is a reuptake inhibitor for the norepinephrine and dopamine receptors. A psychoactive substance, it displays stimulant properties, and effects may include euphoria, heightened awareness, increased energy, and elevated alertness.

description :

3,4-Methylenedioxypyrovalerone (MDPV) is a designer
drug of the phenethylamine class. MDPV is structurally
related to cathinone, an active alkaloid found in the khat
plant, 3,4-methylenedioxymethamphetamine (MDMA),
methamphetamine, and other Schedule I phenethylamines.
MDPV, like some other substances in this class, is a central
nervous system (CNS) stimulant. MDPV is also reported to
have hallucinogenic effects.

buy MDPV online cheap
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buy MDPV has been shown to bind to recombinant human
dopamine, norepinephrine and serotonin transporters and to
inhibit uptake of the corresponding substrate
neurotransmitter in vitro. MDPV has been shown to inhibit
the rat brain synaptosomal uptake of dopamine and
norepinephrine with high potency but has weak effects on
serotonin uptake in vitro.

It has been demonstrated that
MDPV increases extracellular concentration of dopamine in
rodent brain as measured by in vivo microdialysis technique.
MDPV has been shown to increase locomotor activity,
heart rate and blood pressure in rodents. In drug
discrimination tests, MDPV fully substitutes for
methamphetamine in rats trained to discriminate
methamphetamine from saline. In mice trained to
discriminate MDPV from saline, methamphetamine and
MDMA fully substituted MDPV. Intravenous selfadministration studies have shown that rats readily and dose-dependently self-administer MDPV and extended access leads to escalation of drug intake similar to that reported
for stimulants such as cocaine and methamphetamine.

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